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Thomas Neylan, MD

Working Title

Professor

Preferred Pronouns
He/Him/His
Dr. Neylan is a Professor, In Residence in the Departments of Psychiatry and Neurology at the University of California, San Francisco. He is the Director of the Posttraumatic Stress Disorders (PTSD) Clinic and the Stress and Health Research Program at the San Francisco Veterans Affairs Medical Center. His research has focused on the role of sleep in emotion regulation, cognitive function, and metabolic health, in patients with PTSD and in aging populations with neurodegenerative disorders. He has been a Principal Investigator on multiple funded projects sponsored by the National Institute of Aging, National Institute of Mental Health, the National Institute of Justice, the Department of Defense, the Department of Veterans Affairs, and several foundations.
His current funding includes projects focused on the role of sleep and circadian factors in risk and resilience for developing PTSD and Traumatic Brain Injury in acutely traumatized patients seen in Emergency Departments, a human-animal translational study examining the role of maladaptive myelination as a mechanism underpinning the structural and functional brain abnormalities associated with PTSD, a second project examining maladaptive myelination in a postmortem sample of subjects with PTSD and controls together with matched samples of living subjects studied with MRI, two joint clinical and brain bank studies of sleep/wake regulation in neurodegenerative tauopathies, and a controlled trial of a selective glucocorticoid antagonist in PTSD.

Fear
Sleep
Veterans
Dreams
Sleep Wake Disorders
Psychotherapy
Sleep, REM
Police
Combat Disorders
Sleep Initiation And Maintenance Disorders
Metyrapone
Stress Disorders, Post-Traumatic
Implosive Therapy
Supranuclear Palsy, Progressive
Sleep Aids, Pharmaceutical

  • Laufer Outstanding Scientific Achievement Award, International Society for Traumatic Stress Studies, 2021
  • J. Elliott Royer Award for Academic Psychiatry, UCSF, 2017

June 1, 2019 - March 31, 2029 - Clinical Features and Neuropathological Basis of Sleep Wake Behavior in Alzheimer's and PSP , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AG060477
July 23, 2023 - April 30, 2028 - Investigating Fear System Myelination in PTSD Using In Vivo and Post Mortem Data , Principal Investigator . Sponsor: NIH/NIMH, Sponsor Award ID: 1R01MH132617
January 1, 2022 - December 31, 2026 - Phase IIa Trial of a Selective Glucocorticoid Receptor Antagonist in the Treatment ofVeterans with Posttraumatic Stress Disorder (PTSD) , Principal Investigator . Sponsor: NIH, Sponsor Award ID: I01CX001917
January 1, 2020 - December 31, 2025 - Examining the Effect of Sleep Disruption on Emotion Regulation and Trauma-Related Symptoms in Veterans , Principal Investigator . Sponsor: NIH, Sponsor Award ID: IK2CX002032
August 15, 2019 - May 31, 2025 - Linking Sleep Dysfunction to Tau-related Degeneration across AD Progression , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AG064314
January 11, 2019 - October 31, 2024 - Individual Variation in Effects of Traumatic Stress on Gray Matter Myelin , Principal Investigator . Sponsor: NIH/NIMH, Sponsor Award ID: R01MH115020
June 1, 2019 - June 30, 2024 - Effectiveness Research for Common Mental Disorders in Low and Middle Income Countries: A sequential, multiple assignment randomized trial for non-specialist treatment strategies in Kenya , Co-Investigator . Sponsor: NIH, Sponsor Award ID: R01MH113722
August 10, 2018 - May 31, 2023 - Bioinformatics for post-traumatic stress , Co-Investigator . Sponsor: NIH, Sponsor Award ID: R01MH116156
October 1, 2016 - March 31, 2022 - Improving Mind/Body Health and Functioning with Integrative Exercise , Principal Investigator . Sponsor: NIH, Sponsor Award ID: I01RX001939
September 23, 2016 - July 31, 2021 - Longitudinal Assessment of Post-traumatic Syndromes , Co-Investigator . Sponsor: NIH, Sponsor Award ID: U01MH110925
September 20, 2016 - November 30, 2019 - Improving Frontal Emotion Regulation in PTSD by Targeting Sleep , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R56MH107042
September 30, 2018 - May 31, 2019 - Clinical Features and Neuropathological Basis of Sleep Wake Behavior in Alzheimer's and PSP , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R56AG060477
September 26, 2013 - September 25, 2017 - Sleep in Progressive Supranuclear Palsy , Principal Investigator . Sponsor: Rainwater Charitable Foundation, Sponsor Award ID: unknown
October 1, 2012 - June 30, 2016 - Prediction of Neurocognitive Deficits Associated with Sleep Loss , Principal Investigator . Sponsor: Department of Defense, Sponsor Award ID: W81XWH-11-2-0189
July 1, 2012 - June 30, 2016 - PTSD and the Aging Brain , Principal Investigator . Sponsor: Department of Defense, Sponsor Award ID: W81XWH-11-2-0189
September 1, 2009 - August 31, 2015 - Effect of a Hypocretin/Orexin antagonist on neurocognitive performance , Principal Investigator . Sponsor: Department of Defense, Sponsor Award ID: W81XWH-09-2-0080
October 1, 2010 - September 30, 2014 - Mental Health Research Infrastructure Award , Principal Investigator . Sponsor: Department of Defense, Sponsor Award ID: W81XWH-10-2-0078
June 1, 2011 - August 31, 2013 - Combat PTSD, Cellular Aging, and Atrophy of the Hippocampus , Principal Investigator . Sponsor: Lightfighter Trust, Sponsor Award ID: P0040322
March 1, 2008 - February 28, 2012 - Cognitive Behavioral Treatment of Insomnia in Posttraumatic Stress Disorder , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R34MH077667
April 29, 2005 - March 31, 2010 - Neuroendocrine Regulation of Sleep in PTSD , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01MH073978
September 1, 2007 - October 31, 2009 - Biological Pathways Expressed in PTSD , Principal Investigator . Sponsor: Department of Defense, Sponsor Award ID: W81XWH-05-2-0094
August 1, 1998 - July 31, 2004 - SLEEP AND AROUSAL DISTURBANCES IN PTSD , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R29MH057157

Contact information

1550 Fourth Street, #282
San Francisco, CA 94158
United States